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Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats

Our objective was to determine if the insulin-sensitizing drug pioglitazone acutely reduces insulin secretion and causes metabolic deceleration in vivo independently of change in insulin sensitivity. We assessed glucose homeostasis by hyperinsulinemic-euglycemic and hyperglycemic clamp studies and e...

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Detalles Bibliográficos
Autores principales:	Lamontagne, Julien, Jalbert-Arsenault, Élise, Pepin, Émilie, Peyot, Marie-Line, Ruderman, Neil B., Nolan, Christopher J., Joly, Erik, Madiraju, S.R. Murthy, Poitout, Vincent, Prentki, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661607/ https://www.ncbi.nlm.nih.gov/pubmed/23378607 http://dx.doi.org/10.2337/db12-0428

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