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Activation of PPARα Ameliorates Hepatic Insulin Resistance and Steatosis in High Fructose–Fed Mice Despite Increased Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) stress is suggested to cause hepatic insulin resistance by increasing de novo lipogenesis (DNL) and directly interfering with insulin signaling through the activation of the c-Jun N-terminal kinase (JNK) and IκB kinase (IKK) pathway. The current study interrogated these tw...

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Detalles Bibliográficos
Autores principales:	Chan, Stanley M.H., Sun, Ruo-Qiong, Zeng, Xiao-Yi, Choong, Zi-Heng, Wang, Hao, Watt, Matthew J., Ye, Ji-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661626/ https://www.ncbi.nlm.nih.gov/pubmed/23349482 http://dx.doi.org/10.2337/db12-1397

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