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Link Between GIP and Osteopontin in Adipose Tissue and Insulin Resistance
Low-grade inflammation in obesity is associated with accumulation of the macrophage-derived cytokine osteopontin (OPN) in adipose tissue and induction of local as well as systemic insulin resistance. Since glucose-dependent insulinotropic polypeptide (GIP) is a strong stimulator of adipogenesis and...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661641/ https://www.ncbi.nlm.nih.gov/pubmed/23349498 http://dx.doi.org/10.2337/db12-0976 |