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Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans
The role of free fatty acid receptor 1 (FFAR1/GPR40) in glucose homeostasis is still incompletely understood. Small receptor agonists stimulating insulin secretion are undergoing investigation for the treatment of type 2 diabetes. Surprisingly, genome-wide association studies did not discover diabet...
Autores principales: | Wagner, Robert, Kaiser, Gabriele, Gerst, Felicia, Christiansen, Elisabeth, Due-Hansen, Maria E., Grundmann, Manuel, Machicao, Fausto, Peter, Andreas, Kostenis, Evi, Ulven, Trond, Fritsche, Andreas, Häring, Hans-Ulrich, Ullrich, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661642/ https://www.ncbi.nlm.nih.gov/pubmed/23378609 http://dx.doi.org/10.2337/db12-1249 |
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