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The Protective Effects of CD39 Overexpression in Multiple Low-Dose Streptozotocin–Induced Diabetes in Mice

Islet allograft survival limits the long-term success of islet transplantation as a potential curative therapy for type 1 diabetes. A number of factors compromise islet survival, including recurrent diabetes. We investigated whether CD39, an ectonucleotidase that promotes the generation of extracell...

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Detalles Bibliográficos
Autores principales: Chia, Joanne S.J., McRae, Jennifer L., Thomas, Helen E., Fynch, Stacey, Elkerbout, Lorraine, Hill, Prue, Murray-Segal, Lisa, Robson, Simon C., Chen, Jiang-Fan, d’Apice, Anthony J.F., Cowan, Peter J., Dwyer, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661652/
https://www.ncbi.nlm.nih.gov/pubmed/23364452
http://dx.doi.org/10.2337/db12-0625