TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression

Proliferation of pancreatic β-cells is an important mechanism underlying β-cell mass adaptation to metabolic demands. Increasing β-cell mass by regeneration may ameliorate or correct both type 1 and type 2 diabetes, which both result from inadequate production of insulin by β-cells of the pancreatic...

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Detalles Bibliográficos
Autores principales: Suzuki, Tomoyuki, Dai, Ping, Hatakeyama, Tomoya, Harada, Yoshinori, Tanaka, Hideo, Yoshimura, Norio, Takamatsu, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Histochemistry and Cytochemistry 2013
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661777/
https://www.ncbi.nlm.nih.gov/pubmed/23720603
http://dx.doi.org/10.1267/ahc.12035

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