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Etiology, pathophysiology and classifications of the diabetic Charcot foot
In people with diabetes mellitus, the Charcot foot is a specific manifestation of peripheral neuropathy that may involve autonomic neuropathy with high blood flow to the foot, leading to increased bone resorption. It may also involve peripheral somatic polyneuropathy with loss of protective sensatio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661901/ https://www.ncbi.nlm.nih.gov/pubmed/23705058 http://dx.doi.org/10.3402/dfa.v4i0.20872 |
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author | Papanas, Nikolaos Maltezos, Efstratios |
author_facet | Papanas, Nikolaos Maltezos, Efstratios |
author_sort | Papanas, Nikolaos |
collection | PubMed |
description | In people with diabetes mellitus, the Charcot foot is a specific manifestation of peripheral neuropathy that may involve autonomic neuropathy with high blood flow to the foot, leading to increased bone resorption. It may also involve peripheral somatic polyneuropathy with loss of protective sensation and high risk of unrecognized acute or chronic minor trauma. In both cases, there is excess local inflammatory response to foot injury, resulting in local osteoporosis. In the Charcot foot, the acute and chronic phases have been described. The former is characterized by local erythema, edema, and marked temperature elevation, while pain is not a prominent symptom. In the latter, signs of inflammation gradually recede and deformities may develop, increasing the risk of foot ulceration. The most common anatomical classification describes five patterns, according to the localization of bone and joint pathology. This review article aims to provide a brief overview of the diabetic Charcot foot in terms of etiology, pathophysiology, and classification. |
format | Online Article Text |
id | pubmed-3661901 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Co-Action Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-36619012013-05-23 Etiology, pathophysiology and classifications of the diabetic Charcot foot Papanas, Nikolaos Maltezos, Efstratios Diabet Foot Ankle Review Article In people with diabetes mellitus, the Charcot foot is a specific manifestation of peripheral neuropathy that may involve autonomic neuropathy with high blood flow to the foot, leading to increased bone resorption. It may also involve peripheral somatic polyneuropathy with loss of protective sensation and high risk of unrecognized acute or chronic minor trauma. In both cases, there is excess local inflammatory response to foot injury, resulting in local osteoporosis. In the Charcot foot, the acute and chronic phases have been described. The former is characterized by local erythema, edema, and marked temperature elevation, while pain is not a prominent symptom. In the latter, signs of inflammation gradually recede and deformities may develop, increasing the risk of foot ulceration. The most common anatomical classification describes five patterns, according to the localization of bone and joint pathology. This review article aims to provide a brief overview of the diabetic Charcot foot in terms of etiology, pathophysiology, and classification. Co-Action Publishing 2013-05-21 /pmc/articles/PMC3661901/ /pubmed/23705058 http://dx.doi.org/10.3402/dfa.v4i0.20872 Text en © 2013 Nikolaos Papanas and Efstratios Maltezos http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Papanas, Nikolaos Maltezos, Efstratios Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title | Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title_full | Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title_fullStr | Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title_full_unstemmed | Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title_short | Etiology, pathophysiology and classifications of the diabetic Charcot foot |
title_sort | etiology, pathophysiology and classifications of the diabetic charcot foot |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661901/ https://www.ncbi.nlm.nih.gov/pubmed/23705058 http://dx.doi.org/10.3402/dfa.v4i0.20872 |
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