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Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea

BACKGROUND/AIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions. METHODS: In total, 4,023 subjects were enrolled at eight hospit...

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Autores principales: Joo, Young-Eun, Park, Hyun-Kyung, Myung, Dae-Seong, Baik, Gwang-Ho, Shin, Jeong-Eun, Seo, Geom-Seog, Kim, Gwang Ha, Kim, Heung Up, Kim, Hyun Young, Cho, Sung-Il, Kim, Nayoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661962/
https://www.ncbi.nlm.nih.gov/pubmed/23710311
http://dx.doi.org/10.5009/gnl.2013.7.3.303
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author Joo, Young-Eun
Park, Hyun-Kyung
Myung, Dae-Seong
Baik, Gwang-Ho
Shin, Jeong-Eun
Seo, Geom-Seog
Kim, Gwang Ha
Kim, Heung Up
Kim, Hyun Young
Cho, Sung-Il
Kim, Nayoung
author_facet Joo, Young-Eun
Park, Hyun-Kyung
Myung, Dae-Seong
Baik, Gwang-Ho
Shin, Jeong-Eun
Seo, Geom-Seog
Kim, Gwang Ha
Kim, Heung Up
Kim, Hyun Young
Cho, Sung-Il
Kim, Nayoung
author_sort Joo, Young-Eun
collection PubMed
description BACKGROUND/AIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions. METHODS: In total, 4,023 subjects were enrolled at eight hospitals in Korea. AG and IM were diagnosed by endoscopy. Helicobacter pylori immunoglobulin G antibodies were measured. RESULTS: The prevalences of endoscopic AG and IM were 40.7% and 12.5%. In a multivariate analysis, the risk factors for AG were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, IM, and education below the college level (odds ratio [OR], 2.55, 5.00, 1.38, 1.41, 4.29, and 1.35, respectively). The risk factors for IM were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, AG, having relatives with gastric cancer, education below the college level and consumption of dairy products (OR, 3.16, 3.25, 1.88, 2.17, 3.68, 1.48, 1.47, and 1.40, respectively). CONCLUSIONS: A nationwide survey regarding the prevalence of endoscopic AG and IM and their risk factors in Korea supports the hypothesis that endoscopic diagnosis of these premalignant lesions could be helpful to describe a group at high risk for gastric cancer.
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publisher The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer
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spelling pubmed-36619622013-05-24 Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea Joo, Young-Eun Park, Hyun-Kyung Myung, Dae-Seong Baik, Gwang-Ho Shin, Jeong-Eun Seo, Geom-Seog Kim, Gwang Ha Kim, Heung Up Kim, Hyun Young Cho, Sung-Il Kim, Nayoung Gut Liver Original Article BACKGROUND/AIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions. METHODS: In total, 4,023 subjects were enrolled at eight hospitals in Korea. AG and IM were diagnosed by endoscopy. Helicobacter pylori immunoglobulin G antibodies were measured. RESULTS: The prevalences of endoscopic AG and IM were 40.7% and 12.5%. In a multivariate analysis, the risk factors for AG were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, IM, and education below the college level (odds ratio [OR], 2.55, 5.00, 1.38, 1.41, 4.29, and 1.35, respectively). The risk factors for IM were age groups of 40 to 59 years and >60 years, male sex, positive H. pylori serology, AG, having relatives with gastric cancer, education below the college level and consumption of dairy products (OR, 3.16, 3.25, 1.88, 2.17, 3.68, 1.48, 1.47, and 1.40, respectively). CONCLUSIONS: A nationwide survey regarding the prevalence of endoscopic AG and IM and their risk factors in Korea supports the hypothesis that endoscopic diagnosis of these premalignant lesions could be helpful to describe a group at high risk for gastric cancer. The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2013-05 2013-05-13 /pmc/articles/PMC3661962/ /pubmed/23710311 http://dx.doi.org/10.5009/gnl.2013.7.3.303 Text en Copyright © 2013 by the Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Joo, Young-Eun
Park, Hyun-Kyung
Myung, Dae-Seong
Baik, Gwang-Ho
Shin, Jeong-Eun
Seo, Geom-Seog
Kim, Gwang Ha
Kim, Heung Up
Kim, Hyun Young
Cho, Sung-Il
Kim, Nayoung
Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title_full Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title_fullStr Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title_full_unstemmed Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title_short Prevalence and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia: A Nationwide Multicenter Prospective Study in Korea
title_sort prevalence and risk factors of atrophic gastritis and intestinal metaplasia: a nationwide multicenter prospective study in korea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661962/
https://www.ncbi.nlm.nih.gov/pubmed/23710311
http://dx.doi.org/10.5009/gnl.2013.7.3.303
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