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Kidney tubular β-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication
Activation of β-catenin, the principal mediator of canonical Wnt signaling, is a common pathologic finding in a wide variety of chronic kidney diseases (CKD). While β-catenin is induced predominantly in renal tubular epithelium in CKD, surprisingly, depletion of tubular β-catenin had little effect o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662012/ https://www.ncbi.nlm.nih.gov/pubmed/23698793 http://dx.doi.org/10.1038/srep01878 |