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Effect of Ketoconazole, a Cytochrome P450 Inhibitor, on the Efficacy of Quinine and Halofantrine against Schistosoma mansoni in Mice

The fear that schistosomes will become resistant to praziquantel (PZQ) motivates the search for alternatives to treat schistosomiasis. The antimalarials quinine (QN) and halofantrine (HF) possess moderate antischistosomal properties. The major metabolic pathway of QN and HF is through cytochrome P45...

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Detalles Bibliográficos
Autores principales:	Seif el-Din, Sayed Hassan, Sabra, Abdel-Nasser Abdel-Aal, Hammam, Olfat Ali, El-Lakkany, Naglaa Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Parasitology and Tropical Medicine 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662059/ https://www.ncbi.nlm.nih.gov/pubmed/23710083 http://dx.doi.org/10.3347/kjp.2013.51.2.165

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