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A juvenile case of conjunctival atypical nevus

VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share som...

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Autores principales: Colarossi, Cristina, Milazzo, Mario, Paglierani, Milena, Massi, Daniela, Memeo, Lorenzo, Canzonieri, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662158/
https://www.ncbi.nlm.nih.gov/pubmed/23607499
http://dx.doi.org/10.1186/1746-1596-8-64
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author Colarossi, Cristina
Milazzo, Mario
Paglierani, Milena
Massi, Daniela
Memeo, Lorenzo
Canzonieri, Vincenzo
author_facet Colarossi, Cristina
Milazzo, Mario
Paglierani, Milena
Massi, Daniela
Memeo, Lorenzo
Canzonieri, Vincenzo
author_sort Colarossi, Cristina
collection PubMed
description VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share some atypical histological features with nevi found in other anatomic sites like the genital and acral regions, globally designated as nevi with site-related atypia. Moreover, in children and adolescents, rapidly growing conjunctival nevi show sometimes worrisome histological patterns in association with a prominent inflammatory infiltrate that may lead to diagnostic problems. In this paper we describe a juvenile compound nevus characterized by marked melanocytic atypia and severe inflammation, which can be considered a rare case of juvenile conjunctival atypical nevus. The final diagnosis relied on morphological and immunohistochemical characterization of the large epithelioid melanocytic cells, and on the results of FISH analysis.
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spelling pubmed-36621582013-05-24 A juvenile case of conjunctival atypical nevus Colarossi, Cristina Milazzo, Mario Paglierani, Milena Massi, Daniela Memeo, Lorenzo Canzonieri, Vincenzo Diagn Pathol Case Report VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share some atypical histological features with nevi found in other anatomic sites like the genital and acral regions, globally designated as nevi with site-related atypia. Moreover, in children and adolescents, rapidly growing conjunctival nevi show sometimes worrisome histological patterns in association with a prominent inflammatory infiltrate that may lead to diagnostic problems. In this paper we describe a juvenile compound nevus characterized by marked melanocytic atypia and severe inflammation, which can be considered a rare case of juvenile conjunctival atypical nevus. The final diagnosis relied on morphological and immunohistochemical characterization of the large epithelioid melanocytic cells, and on the results of FISH analysis. BioMed Central 2013-04-22 /pmc/articles/PMC3662158/ /pubmed/23607499 http://dx.doi.org/10.1186/1746-1596-8-64 Text en Copyright © 2013 Colarossi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Colarossi, Cristina
Milazzo, Mario
Paglierani, Milena
Massi, Daniela
Memeo, Lorenzo
Canzonieri, Vincenzo
A juvenile case of conjunctival atypical nevus
title A juvenile case of conjunctival atypical nevus
title_full A juvenile case of conjunctival atypical nevus
title_fullStr A juvenile case of conjunctival atypical nevus
title_full_unstemmed A juvenile case of conjunctival atypical nevus
title_short A juvenile case of conjunctival atypical nevus
title_sort juvenile case of conjunctival atypical nevus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662158/
https://www.ncbi.nlm.nih.gov/pubmed/23607499
http://dx.doi.org/10.1186/1746-1596-8-64
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