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A juvenile case of conjunctival atypical nevus
VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share som...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662158/ https://www.ncbi.nlm.nih.gov/pubmed/23607499 http://dx.doi.org/10.1186/1746-1596-8-64 |
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author | Colarossi, Cristina Milazzo, Mario Paglierani, Milena Massi, Daniela Memeo, Lorenzo Canzonieri, Vincenzo |
author_facet | Colarossi, Cristina Milazzo, Mario Paglierani, Milena Massi, Daniela Memeo, Lorenzo Canzonieri, Vincenzo |
author_sort | Colarossi, Cristina |
collection | PubMed |
description | VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share some atypical histological features with nevi found in other anatomic sites like the genital and acral regions, globally designated as nevi with site-related atypia. Moreover, in children and adolescents, rapidly growing conjunctival nevi show sometimes worrisome histological patterns in association with a prominent inflammatory infiltrate that may lead to diagnostic problems. In this paper we describe a juvenile compound nevus characterized by marked melanocytic atypia and severe inflammation, which can be considered a rare case of juvenile conjunctival atypical nevus. The final diagnosis relied on morphological and immunohistochemical characterization of the large epithelioid melanocytic cells, and on the results of FISH analysis. |
format | Online Article Text |
id | pubmed-3662158 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-36621582013-05-24 A juvenile case of conjunctival atypical nevus Colarossi, Cristina Milazzo, Mario Paglierani, Milena Massi, Daniela Memeo, Lorenzo Canzonieri, Vincenzo Diagn Pathol Case Report VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2973228795724608 Melanocytic nevi are the most common tumors of the conjunctiva, accounting for 28% of all neoplastic lesions. These tumors, despite their benign behavior, share some atypical histological features with nevi found in other anatomic sites like the genital and acral regions, globally designated as nevi with site-related atypia. Moreover, in children and adolescents, rapidly growing conjunctival nevi show sometimes worrisome histological patterns in association with a prominent inflammatory infiltrate that may lead to diagnostic problems. In this paper we describe a juvenile compound nevus characterized by marked melanocytic atypia and severe inflammation, which can be considered a rare case of juvenile conjunctival atypical nevus. The final diagnosis relied on morphological and immunohistochemical characterization of the large epithelioid melanocytic cells, and on the results of FISH analysis. BioMed Central 2013-04-22 /pmc/articles/PMC3662158/ /pubmed/23607499 http://dx.doi.org/10.1186/1746-1596-8-64 Text en Copyright © 2013 Colarossi et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Colarossi, Cristina Milazzo, Mario Paglierani, Milena Massi, Daniela Memeo, Lorenzo Canzonieri, Vincenzo A juvenile case of conjunctival atypical nevus |
title | A juvenile case of conjunctival atypical nevus |
title_full | A juvenile case of conjunctival atypical nevus |
title_fullStr | A juvenile case of conjunctival atypical nevus |
title_full_unstemmed | A juvenile case of conjunctival atypical nevus |
title_short | A juvenile case of conjunctival atypical nevus |
title_sort | juvenile case of conjunctival atypical nevus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662158/ https://www.ncbi.nlm.nih.gov/pubmed/23607499 http://dx.doi.org/10.1186/1746-1596-8-64 |
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