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Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio

Zerumbone (ZER) isolated from Zingiber zerumbet was previously encapsulated with hydroxypropyl-β-cyclodextrin (HPβCD) to enhance ZER's solubility in water, thus making it highly tolerable in the human body. The anticancer effects of this new ZER-HPβCD inclusion complex via apoptosis cell death...

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Detalles Bibliográficos
Autores principales: Muhammad Nadzri, Nabilah, Abdul, Ahmad Bustamam, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim, Eid, Eltayeb E. M., Mohan, Syam, Kamalidehghan, Behnam, Anasamy, Theebaa, Ng, Kuan Beng, Syam, Suvitha, Arbab, Ismail Adam, Rahman, Heshu Sulaiman, Ali, Hapipah Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662198/
https://www.ncbi.nlm.nih.gov/pubmed/23737847
http://dx.doi.org/10.1155/2013/810632

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