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Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia
BACKGROUND: The aim of this study was to investigate the link between atrial fibrillation (AF) and dyspepsia, as well as the contribution of dyspepsia to the overall burden of AF. METHODS: The 2008, 2009, and 2010 Japan National Health and Wellness Survey (NHWS) datasets were used in this study. The...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662464/ https://www.ncbi.nlm.nih.gov/pubmed/23717048 http://dx.doi.org/10.2147/CEG.S39628 |
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author | Kinoshita, Yoshikazu DiBonaventura, Marco Rossi, Bruno Iwamoto, Kazuya Wang, Edward C Y Briere, Jean-Baptiste |
author_facet | Kinoshita, Yoshikazu DiBonaventura, Marco Rossi, Bruno Iwamoto, Kazuya Wang, Edward C Y Briere, Jean-Baptiste |
author_sort | Kinoshita, Yoshikazu |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate the link between atrial fibrillation (AF) and dyspepsia, as well as the contribution of dyspepsia to the overall burden of AF. METHODS: The 2008, 2009, and 2010 Japan National Health and Wellness Survey (NHWS) datasets were used in this study. The NHWS is an Internet-based survey administered to the adult population in Japan using a random stratified sampling framework to ensure demographic representativeness. The presence of dyspepsia was compared between those with and without AF. Among those with AF, the effect of dyspepsia on health status, work productivity, and activity impairment was examined, along with health care resource use using multivariable regression modeling and controlling for baseline differences. RESULTS: Among patients with AF (n = 565), the three most commonly reported comorbidities were hypertension (38.76%), dyspepsia (37.35%), and overactive bladder (28.72%). Patients with AF had 48.59% greater odds of reporting dyspepsia than those without AF (P < 0.05). Patients with dyspepsia used more AF medications (2.05 versus 1.54) and had been diagnosed more recently (9.97 versus 10.58 years). Dyspepsia was associated with significantly worse physical health status (P < 0.05) and significantly more absenteeism, overall work impairment, activity impairment, physician visits, and emergency room visits (all P < 0.05). CONCLUSION: Patients with AF in Japan experience a number of comorbidities, with dyspepsia being the most common noncardiovascular comorbidity. Given the prevalence and additional burden of this comorbidity across both humanistic and economic outcomes, the management of dyspepsia among patients with AF should be an area of greater focus. |
format | Online Article Text |
id | pubmed-3662464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-36624642013-05-28 Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia Kinoshita, Yoshikazu DiBonaventura, Marco Rossi, Bruno Iwamoto, Kazuya Wang, Edward C Y Briere, Jean-Baptiste Clin Exp Gastroenterol Original Research BACKGROUND: The aim of this study was to investigate the link between atrial fibrillation (AF) and dyspepsia, as well as the contribution of dyspepsia to the overall burden of AF. METHODS: The 2008, 2009, and 2010 Japan National Health and Wellness Survey (NHWS) datasets were used in this study. The NHWS is an Internet-based survey administered to the adult population in Japan using a random stratified sampling framework to ensure demographic representativeness. The presence of dyspepsia was compared between those with and without AF. Among those with AF, the effect of dyspepsia on health status, work productivity, and activity impairment was examined, along with health care resource use using multivariable regression modeling and controlling for baseline differences. RESULTS: Among patients with AF (n = 565), the three most commonly reported comorbidities were hypertension (38.76%), dyspepsia (37.35%), and overactive bladder (28.72%). Patients with AF had 48.59% greater odds of reporting dyspepsia than those without AF (P < 0.05). Patients with dyspepsia used more AF medications (2.05 versus 1.54) and had been diagnosed more recently (9.97 versus 10.58 years). Dyspepsia was associated with significantly worse physical health status (P < 0.05) and significantly more absenteeism, overall work impairment, activity impairment, physician visits, and emergency room visits (all P < 0.05). CONCLUSION: Patients with AF in Japan experience a number of comorbidities, with dyspepsia being the most common noncardiovascular comorbidity. Given the prevalence and additional burden of this comorbidity across both humanistic and economic outcomes, the management of dyspepsia among patients with AF should be an area of greater focus. Dove Medical Press 2013-05-20 /pmc/articles/PMC3662464/ /pubmed/23717048 http://dx.doi.org/10.2147/CEG.S39628 Text en © 2013 Kinoshita et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Kinoshita, Yoshikazu DiBonaventura, Marco Rossi, Bruno Iwamoto, Kazuya Wang, Edward C Y Briere, Jean-Baptiste Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title | Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title_full | Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title_fullStr | Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title_full_unstemmed | Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title_short | Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia |
title_sort | burden of comorbidities among japanese patients with atrial fibrillation: a case study of dyspepsia |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662464/ https://www.ncbi.nlm.nih.gov/pubmed/23717048 http://dx.doi.org/10.2147/CEG.S39628 |
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