Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

Disrupting erythrocyte invasion by Plasmodium falciparum is an attractive approach to combat malaria. P. falciparum EBA-175 (PfEBA-175) engages the host receptor Glycophorin A (GpA) during invasion and is a leading vaccine candidate. Antibodies that recognize PfEBA-175 can prevent parasite growth, a...

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Detalles Bibliográficos
Autores principales: Chen, Edwin, Paing, May M., Salinas, Nichole, Sim, B. Kim Lee, Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662668/
https://www.ncbi.nlm.nih.gov/pubmed/23717209
http://dx.doi.org/10.1371/journal.ppat.1003390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662668/
https://www.ncbi.nlm.nih.gov/pubmed/23717209
http://dx.doi.org/10.1371/journal.ppat.1003390

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