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Human Papillomavirus (HPV) Upregulates the Cellular Deubiquitinase UCHL1 to Suppress the Keratinocyte's Innate Immune Response
Persistent infection of basal keratinocytes with high-risk human papillomavirus (hrHPV) may cause cancer. Keratinocytes are equipped with different pattern recognition receptors (PRRs) but hrHPV has developed ways to dampen their signals resulting in minimal inflammation and evasion of host immunity...
Autores principales: | Karim, Rezaul, Tummers, Bart, Meyers, Craig, Biryukov, Jennifer L., Alam, Samina, Backendorf, Claude, Jha, Veena, Offringa, Rienk, van Ommen, Gert-Jan B., Melief, Cornelis J. M., Guardavaccaro, Daniele, Boer, Judith M., van der Burg, Sjoerd H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662672/ https://www.ncbi.nlm.nih.gov/pubmed/23717208 http://dx.doi.org/10.1371/journal.ppat.1003384 |
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