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Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men
BACKGROUND: Men who have sex with men (MSM) were found to be one of the high-risk populations for Entamoeba histolytica (E. histolytica) infection. Accompanied by the prevalence of human immunodeficiency virus (HIV) among MSM, invasive amebiasis caused by E. histolytica has been paid attention to as...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662687/ https://www.ncbi.nlm.nih.gov/pubmed/23717699 http://dx.doi.org/10.1371/journal.pntd.0002232 |
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author | Zhou, Feng Li, Mufei Li, Xiangwei Yang, Yu Gao, Cong Jin, Qi Gao, Lei |
author_facet | Zhou, Feng Li, Mufei Li, Xiangwei Yang, Yu Gao, Cong Jin, Qi Gao, Lei |
author_sort | Zhou, Feng |
collection | PubMed |
description | BACKGROUND: Men who have sex with men (MSM) were found to be one of the high-risk populations for Entamoeba histolytica (E. histolytica) infection. Accompanied by the prevalence of human immunodeficiency virus (HIV) among MSM, invasive amebiasis caused by E. histolytica has been paid attention to as an opportunistic parasitic infection. However, the status of E. histolytica infection among MSM has been barely studied in mainland China. METHODS: Seroprevalance of E. histolytica was determined using an enzyme-linked immunosorbent assay based on a cross-sectional study conducted in Beijing and Tianjin, China. Factors potentially associated with E. histolytica infection were identified by logistic regression analysis. RESULTS: A total of 602 MSM were included in the study and the laboratory data on serostatus of E. histolytica were available for 599 of them (99.5%). 246 (41.1%) and 51 (8.5%) of the study participants were E. histolytica seropositive and HIV seropositive, respectively. Univariate analyses suggested preferred anal sex behaviors were associated with E. histolytica seropositivity. In multivariate logistic regression analysis, “only has receptive anal sex” (OR: 2.03; 95% CI: 1.22 3.37), “majority receptive anal sex” (OR: 1.83; 95% CI: 1.13, 2.95), and “sadomasochistic behavior (SM)” (OR: 2.30; 95% CI: 1.04, 5.13) were found to be significantly associated with E. histolytica infection. CONCLUSIONS: High seroprevalence of E. histolytica infection was observed among MSM from Beijing and Tianjin, China. Receptive anal sex behavior and SM were identified as potential predictors. Therefore, E. histolytica and HIV co-infection needs to be concerned among MSM due to their sharing the common risk behaviors. |
format | Online Article Text |
id | pubmed-3662687 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-36626872013-05-28 Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men Zhou, Feng Li, Mufei Li, Xiangwei Yang, Yu Gao, Cong Jin, Qi Gao, Lei PLoS Negl Trop Dis Research Article BACKGROUND: Men who have sex with men (MSM) were found to be one of the high-risk populations for Entamoeba histolytica (E. histolytica) infection. Accompanied by the prevalence of human immunodeficiency virus (HIV) among MSM, invasive amebiasis caused by E. histolytica has been paid attention to as an opportunistic parasitic infection. However, the status of E. histolytica infection among MSM has been barely studied in mainland China. METHODS: Seroprevalance of E. histolytica was determined using an enzyme-linked immunosorbent assay based on a cross-sectional study conducted in Beijing and Tianjin, China. Factors potentially associated with E. histolytica infection were identified by logistic regression analysis. RESULTS: A total of 602 MSM were included in the study and the laboratory data on serostatus of E. histolytica were available for 599 of them (99.5%). 246 (41.1%) and 51 (8.5%) of the study participants were E. histolytica seropositive and HIV seropositive, respectively. Univariate analyses suggested preferred anal sex behaviors were associated with E. histolytica seropositivity. In multivariate logistic regression analysis, “only has receptive anal sex” (OR: 2.03; 95% CI: 1.22 3.37), “majority receptive anal sex” (OR: 1.83; 95% CI: 1.13, 2.95), and “sadomasochistic behavior (SM)” (OR: 2.30; 95% CI: 1.04, 5.13) were found to be significantly associated with E. histolytica infection. CONCLUSIONS: High seroprevalence of E. histolytica infection was observed among MSM from Beijing and Tianjin, China. Receptive anal sex behavior and SM were identified as potential predictors. Therefore, E. histolytica and HIV co-infection needs to be concerned among MSM due to their sharing the common risk behaviors. Public Library of Science 2013-05-23 /pmc/articles/PMC3662687/ /pubmed/23717699 http://dx.doi.org/10.1371/journal.pntd.0002232 Text en © 2013 Zhou et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Zhou, Feng Li, Mufei Li, Xiangwei Yang, Yu Gao, Cong Jin, Qi Gao, Lei Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title | Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title_full | Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title_fullStr | Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title_full_unstemmed | Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title_short | Seroprevalence of Entamoeba histolytica Infection among Chinese Men Who Have Sex with Men |
title_sort | seroprevalence of entamoeba histolytica infection among chinese men who have sex with men |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662687/ https://www.ncbi.nlm.nih.gov/pubmed/23717699 http://dx.doi.org/10.1371/journal.pntd.0002232 |
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