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Inference of Gene Regulatory Networks with Sparse Structural Equation Models Exploiting Genetic Perturbations
Integrating genetic perturbations with gene expression data not only improves accuracy of regulatory network topology inference, but also enables learning of causal regulatory relations between genes. Although a number of methods have been developed to integrate both types of data, the desiderata of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662697/ https://www.ncbi.nlm.nih.gov/pubmed/23717196 http://dx.doi.org/10.1371/journal.pcbi.1003068 |