Inference of Gene Regulatory Networks with Sparse Structural Equation Models Exploiting Genetic Perturbations

Integrating genetic perturbations with gene expression data not only improves accuracy of regulatory network topology inference, but also enables learning of causal regulatory relations between genes. Although a number of methods have been developed to integrate both types of data, the desiderata of...

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Detalles Bibliográficos
Autores principales: Cai, Xiaodong, Bazerque, Juan Andrés, Giannakis, Georgios B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662697/
https://www.ncbi.nlm.nih.gov/pubmed/23717196
http://dx.doi.org/10.1371/journal.pcbi.1003068

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