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Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex

In frontalized mammals it has been demonstrated that adaptation produces shift of the peak of the orientation tuning curve of neuron following frequent or lengthier presentation of a non-preferred stimulus. Depending on the duration of adaptation the shift is attractive (toward the adapter) or repul...

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Autores principales: Jeyabalaratnam, Jeyadarshan, Bharmauria, Vishal, Bachatene, Lyes, Cattan, Sarah, Angers, Annie, Molotchnikoff, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662720/
https://www.ncbi.nlm.nih.gov/pubmed/23717586
http://dx.doi.org/10.1371/journal.pone.0064294
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author Jeyabalaratnam, Jeyadarshan
Bharmauria, Vishal
Bachatene, Lyes
Cattan, Sarah
Angers, Annie
Molotchnikoff, Stéphane
author_facet Jeyabalaratnam, Jeyadarshan
Bharmauria, Vishal
Bachatene, Lyes
Cattan, Sarah
Angers, Annie
Molotchnikoff, Stéphane
author_sort Jeyabalaratnam, Jeyadarshan
collection PubMed
description In frontalized mammals it has been demonstrated that adaptation produces shift of the peak of the orientation tuning curve of neuron following frequent or lengthier presentation of a non-preferred stimulus. Depending on the duration of adaptation the shift is attractive (toward the adapter) or repulsive (away from the adapter). Mouse exhibits a salt-and-pepper cortical organization of orientation maps, hence this species may respond differently to adaptation. To examine this question, we determined the effect of twelve minutes of adaptation to one particular orientation on neuronal orientation tuning curves in V1 of anesthetized mice. Multi-unit activity of neurons in V1 was recorded in a conventional fashion. Cells were stimulated with sine-wave drifting gratings whose orientation tilted in steps. Results revealed that similarly to cats and monkeys, majority of cells shifted their optimal orientation in the direction of the adapter while a small proportion exhibited a repulsive shift. Moreover, initially untuned cells showing poor tuning curves reacted to adaptation by displaying sharp orientation selectivity. It seems that modification of the cellular property following adaptation is a general phenomenon observed in all mammals in spite of the different organization pattern of the visual cortex. This study is of pertinence to comprehend the mechanistic pathways of brain plasticity.
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spelling pubmed-36627202013-05-28 Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex Jeyabalaratnam, Jeyadarshan Bharmauria, Vishal Bachatene, Lyes Cattan, Sarah Angers, Annie Molotchnikoff, Stéphane PLoS One Research Article In frontalized mammals it has been demonstrated that adaptation produces shift of the peak of the orientation tuning curve of neuron following frequent or lengthier presentation of a non-preferred stimulus. Depending on the duration of adaptation the shift is attractive (toward the adapter) or repulsive (away from the adapter). Mouse exhibits a salt-and-pepper cortical organization of orientation maps, hence this species may respond differently to adaptation. To examine this question, we determined the effect of twelve minutes of adaptation to one particular orientation on neuronal orientation tuning curves in V1 of anesthetized mice. Multi-unit activity of neurons in V1 was recorded in a conventional fashion. Cells were stimulated with sine-wave drifting gratings whose orientation tilted in steps. Results revealed that similarly to cats and monkeys, majority of cells shifted their optimal orientation in the direction of the adapter while a small proportion exhibited a repulsive shift. Moreover, initially untuned cells showing poor tuning curves reacted to adaptation by displaying sharp orientation selectivity. It seems that modification of the cellular property following adaptation is a general phenomenon observed in all mammals in spite of the different organization pattern of the visual cortex. This study is of pertinence to comprehend the mechanistic pathways of brain plasticity. Public Library of Science 2013-05-23 /pmc/articles/PMC3662720/ /pubmed/23717586 http://dx.doi.org/10.1371/journal.pone.0064294 Text en © 2013 Jeyabalaratnam et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Jeyabalaratnam, Jeyadarshan
Bharmauria, Vishal
Bachatene, Lyes
Cattan, Sarah
Angers, Annie
Molotchnikoff, Stéphane
Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title_full Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title_fullStr Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title_full_unstemmed Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title_short Adaptation Shifts Preferred Orientation of Tuning Curve in the Mouse Visual Cortex
title_sort adaptation shifts preferred orientation of tuning curve in the mouse visual cortex
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662720/
https://www.ncbi.nlm.nih.gov/pubmed/23717586
http://dx.doi.org/10.1371/journal.pone.0064294
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