Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides

We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-direc...

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Detalles Bibliográficos
Autores principales: Su, Wu, Bagshaw, Clive R., Burley, Glenn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662969/
https://www.ncbi.nlm.nih.gov/pubmed/23703234
http://dx.doi.org/10.1038/srep01883
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author Su, Wu
Bagshaw, Clive R.
Burley, Glenn A.
author_facet Su, Wu
Bagshaw, Clive R.
Burley, Glenn A.
author_sort Su, Wu
collection PubMed
description We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ).
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spelling pubmed-36629692013-05-24 Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides Su, Wu Bagshaw, Clive R. Burley, Glenn A. Sci Rep Article We describe a photonic waveguide where FRET is routed uni-directionally along a double-stranded DNA track. The efficiency of FRET is modulated by the supramolecular control of fluorophores along double-stranded DNA using fluorophore-tethered Pyrrole-Imidazole polyamides (PAs). We show that uni-directional FRET is enhanced by the complete assembly of each of the constituent parts, resulting in the selective routing of light along simple DNA duplexes as well as a three-way junction (3WJ). Nature Publishing Group 2013-05-24 /pmc/articles/PMC3662969/ /pubmed/23703234 http://dx.doi.org/10.1038/srep01883 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Article
Su, Wu
Bagshaw, Clive R.
Burley, Glenn A.
Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title_full Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title_fullStr Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title_full_unstemmed Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title_short Addressable and unidirectional energy transfer along a DNA three-way junction programmed by pyrrole-imidazole polyamides
title_sort addressable and unidirectional energy transfer along a dna three-way junction programmed by pyrrole-imidazole polyamides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662969/
https://www.ncbi.nlm.nih.gov/pubmed/23703234
http://dx.doi.org/10.1038/srep01883
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