A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast

We report a case of Muir-Torre syndrome (MTS) with a very rare combination of cancers, involving bilateral eyelid cancers and breast cancer. A 71-year-old female with a history of breast cancer from 18 years prior presented with bilateral eyelid tumors. One of her siblings had lung cancer, and anoth...

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Detalles Bibliográficos
Autores principales: Kamisasanuki, Taro, Uchino, Eisuke, Fukushima, Jun-ichi, Yoshikawa, Hiroshi, Ishibashi, Tatsuro, Sakamoto, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Ophthalmological Society 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663064/
https://www.ncbi.nlm.nih.gov/pubmed/23730114
http://dx.doi.org/10.3341/kjo.2013.27.3.204
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author Kamisasanuki, Taro
Uchino, Eisuke
Fukushima, Jun-ichi
Yoshikawa, Hiroshi
Ishibashi, Tatsuro
Sakamoto, Taiji
author_facet Kamisasanuki, Taro
Uchino, Eisuke
Fukushima, Jun-ichi
Yoshikawa, Hiroshi
Ishibashi, Tatsuro
Sakamoto, Taiji
author_sort Kamisasanuki, Taro
collection PubMed
description We report a case of Muir-Torre syndrome (MTS) with a very rare combination of cancers, involving bilateral eyelid cancers and breast cancer. A 71-year-old female with a history of breast cancer from 18 years prior presented with bilateral eyelid tumors. One of her siblings had lung cancer, and another had pancreatic cancer. She underwent excisional biopsy of the eyelid tumors and histopathology revealed sebaceous carcinoma of the right eyelid and basal cell carcinoma of the left. She was diagnosed with MTS: a skin cancer associated with visceral malignancy. Immunohistochemical tests for mutS homolog 2 showed a lack of expression in both eyelid carcinomas.
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spelling pubmed-36630642013-06-01 A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast Kamisasanuki, Taro Uchino, Eisuke Fukushima, Jun-ichi Yoshikawa, Hiroshi Ishibashi, Tatsuro Sakamoto, Taiji Korean J Ophthalmol Case Report We report a case of Muir-Torre syndrome (MTS) with a very rare combination of cancers, involving bilateral eyelid cancers and breast cancer. A 71-year-old female with a history of breast cancer from 18 years prior presented with bilateral eyelid tumors. One of her siblings had lung cancer, and another had pancreatic cancer. She underwent excisional biopsy of the eyelid tumors and histopathology revealed sebaceous carcinoma of the right eyelid and basal cell carcinoma of the left. She was diagnosed with MTS: a skin cancer associated with visceral malignancy. Immunohistochemical tests for mutS homolog 2 showed a lack of expression in both eyelid carcinomas. The Korean Ophthalmological Society 2013-06 2013-04-10 /pmc/articles/PMC3663064/ /pubmed/23730114 http://dx.doi.org/10.3341/kjo.2013.27.3.204 Text en © 2013 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kamisasanuki, Taro
Uchino, Eisuke
Fukushima, Jun-ichi
Yoshikawa, Hiroshi
Ishibashi, Tatsuro
Sakamoto, Taiji
A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title_full A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title_fullStr A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title_full_unstemmed A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title_short A Case of Muir-Torre Syndrome with Multiple Cancers of Bilateral Eyelids and Breast
title_sort case of muir-torre syndrome with multiple cancers of bilateral eyelids and breast
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663064/
https://www.ncbi.nlm.nih.gov/pubmed/23730114
http://dx.doi.org/10.3341/kjo.2013.27.3.204
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