A CRISPR way to engineer the human genome

RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an efficient and versatile method for targeted manipulation of mammalian genomes.

Detalles Bibliográficos
Autores principales: Ramalingam, Sivaprakash, Annaluru, Narayana, Chandrasegaran, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663103/
https://www.ncbi.nlm.nih.gov/pubmed/23448668
http://dx.doi.org/10.1186/gb-2013-14-2-107
Descripción
Sumario:RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an efficient and versatile method for targeted manipulation of mammalian genomes.

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