Cargando…
Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms
Translation initiation factor 2 (IF2) is involved in the early steps of bacterial protein synthesis. It promotes the stabilization of the initiator tRNA on the 30S initiation complex (IC) and triggers GTP hydrolysis upon ribosomal subunit joining. While the structure of an archaeal homologue (a/eIF5...
Autores principales: | Simonetti, Angelita, Marzi, Stefano, Fabbretti, Attilio, Hazemann, Isabelle, Jenner, Lasse, Urzhumtsev, Alexandre, Gualerzi, Claudio O., Klaholz, Bruno P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663118/ https://www.ncbi.nlm.nih.gov/pubmed/23695237 http://dx.doi.org/10.1107/S0907444913006422 |
Ejemplares similares
-
E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form
por: Johansen, Jesper S, et al.
Publicado: (2018) -
High-resolution crystal structures of Escherichia coli FtsZ bound to GDP and GTP
por: Schumacher, Maria A., et al.
Publicado: (2020) -
Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations
por: Maruyama, Kei, et al.
Publicado: (2019) -
Translation initiation without IF2-dependent GTP hydrolysis
por: Fabbretti, Attilio, et al.
Publicado: (2012) -
Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding
por: Tomar, Sushil Kumar, et al.
Publicado: (2009)