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Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms

Translation initiation factor 2 (IF2) is involved in the early steps of bacterial protein synthesis. It promotes the stabilization of the initiator tRNA on the 30S initiation complex (IC) and triggers GTP hydrolysis upon ribosomal subunit joining. While the structure of an archaeal homologue (a/eIF5...

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Detalles Bibliográficos
Autores principales: Simonetti, Angelita, Marzi, Stefano, Fabbretti, Attilio, Hazemann, Isabelle, Jenner, Lasse, Urzhumtsev, Alexandre, Gualerzi, Claudio O., Klaholz, Bruno P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663118/
https://www.ncbi.nlm.nih.gov/pubmed/23695237
http://dx.doi.org/10.1107/S0907444913006422

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