STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during Chlamydia trachomatis Infection

STING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent type I IFN response in infected cells, yet the IFN-indu...

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Detalles Bibliográficos
Autores principales: Barker, Jeffrey R., Koestler, Benjamin J., Carpenter, Victoria K., Burdette, Dara L., Waters, Christopher M., Vance, Russell E., Valdivia, Raphael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663186/
https://www.ncbi.nlm.nih.gov/pubmed/23631912
http://dx.doi.org/10.1128/mBio.00018-13

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