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Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans

Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the brain and causing meningoencephalitis. Although urea is not required for synthesis of apourease encoded by URE1, the available nitrogen source affected the expression of URE1 as well as the level of the enzyme a...

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Detalles Bibliográficos
Autores principales: Singh, Arpita, Panting, Robert J., Varma, Ashok, Saijo, Tomomi, Waldron, Kevin J., Jong, Ambrose, Ngamskulrungroj, Popchai, Chang, Yun C., Rutherford, Julian C., Kwon-Chung, Kyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663189/
https://www.ncbi.nlm.nih.gov/pubmed/23653445
http://dx.doi.org/10.1128/mBio.00220-13

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