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Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans
Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the brain and causing meningoencephalitis. Although urea is not required for synthesis of apourease encoded by URE1, the available nitrogen source affected the expression of URE1 as well as the level of the enzyme a...
Autores principales: | Singh, Arpita, Panting, Robert J., Varma, Ashok, Saijo, Tomomi, Waldron, Kevin J., Jong, Ambrose, Ngamskulrungroj, Popchai, Chang, Yun C., Rutherford, Julian C., Kwon-Chung, Kyung J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663189/ https://www.ncbi.nlm.nih.gov/pubmed/23653445 http://dx.doi.org/10.1128/mBio.00220-13 |
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