Transforming growth factor-β1 treatment of oral cancer induces epithelial-mesenchymal transition and promotes bone invasion via enhanced activity of osteoclasts

This study investigates relationships between EMT and bone invasion by OSCC. Three OSCC cell lines, SCC25, HN5, and Tca8113 were artificially induced to display EMT by adding 5 ng/mL of TGF-β1 to culture media for 1–3 days. Cell morphology and phenotypic changes was examined by immunocytochemical st...

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Detalles Bibliográficos
Autores principales: Quan, Jingjing, Elhousiny, Moustafa, Johnson, Newell W., Gao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663202/
https://www.ncbi.nlm.nih.gov/pubmed/23378237
http://dx.doi.org/10.1007/s10585-013-9570-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663202/
https://www.ncbi.nlm.nih.gov/pubmed/23378237
http://dx.doi.org/10.1007/s10585-013-9570-0

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