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Utility of CSF in translational neuroscience
Human cerebrospinal fluid (CSF) sampling is of high value as the only general applicable methodology to obtain information on free drug concentrations in individual human brain. As the ultimate interest is in the free drug concentration at the CNS target site, the question is what CSF concentrations...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663203/ https://www.ncbi.nlm.nih.gov/pubmed/23400635 http://dx.doi.org/10.1007/s10928-013-9301-9 |