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The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT(1A) signalling
RATIONALE: Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new way to achieve antipsychotic-like activity. LSP1-2111, the group III mGlu receptor orthosteric agonist, with a high affinity towards mGlu(4) receptors, was...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663209/ https://www.ncbi.nlm.nih.gov/pubmed/23474845 http://dx.doi.org/10.1007/s00213-013-3005-0 |