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The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT(1A) signalling

RATIONALE: Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new way to achieve antipsychotic-like activity. LSP1-2111, the group III mGlu receptor orthosteric agonist, with a high affinity towards mGlu(4) receptors, was...

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Detalles Bibliográficos
Autores principales:	Wierońska, Joanna M., Acher, Francine C., Sławińska, Anna, Gruca, Piotr, Łasoń-Tyburkiewicz, Magdalena, Papp, Mariusz, Pilc, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2013
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663209/ https://www.ncbi.nlm.nih.gov/pubmed/23474845 http://dx.doi.org/10.1007/s00213-013-3005-0

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