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PIK3CA Mutations in Hepatocellular Carcinoma in Korea

PURPOSE: Phosphatidylinositol 3-kinases/AKT pathway plays a pivotal role in hepatocellular carcinoma (HCC). Mutant PIK3CA, encoding the p110a catalytic subunit, stimulates the AKT pathway and promotes cell growth in various cancers. PIK3CA mutation rate has been usually reported as low frequency (&l...

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Detalles Bibliográficos
Autores principales: Kim, Heesue, Park, Cheol-Keun, Lee, Su Jin, Rha, Sun Young, Park, Kyu Hyun, Lim, Ho Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663228/
https://www.ncbi.nlm.nih.gov/pubmed/23709421
http://dx.doi.org/10.3349/ymj.2013.54.4.883