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Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation

BACKGROUND: Cytomegalovirus is an important infection in kidney Transplantation. Isolation of the CMV virus or detection of its proteins or nucleic acid in any body fluid or tissue specimen is defined as “CMV infection”. CASE PRESENTATION: A 10-year-old girl was admitted frequently for vomiting and...

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Autores principales: Merrikhi, Ali-Reza, Amir-Shahkarami, Seyed-Mohammad, Saneian, Hosein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663317/
https://www.ncbi.nlm.nih.gov/pubmed/23724187
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author Merrikhi, Ali-Reza
Amir-Shahkarami, Seyed-Mohammad
Saneian, Hosein
author_facet Merrikhi, Ali-Reza
Amir-Shahkarami, Seyed-Mohammad
Saneian, Hosein
author_sort Merrikhi, Ali-Reza
collection PubMed
description BACKGROUND: Cytomegalovirus is an important infection in kidney Transplantation. Isolation of the CMV virus or detection of its proteins or nucleic acid in any body fluid or tissue specimen is defined as “CMV infection”. CASE PRESENTATION: A 10-year-old girl was admitted frequently for vomiting and colicky watery diarrhea starting one month after renal transplantation from a non-relative living donor. Cr, BUN, serum electrolytes and also liver function tests were normal. Anti CMV IgM titer was negative before and after transplantation. On colonoscopy large aphthous like lesions were detected in the colon. CMV PCR of the lesion was strongly positive (>2000 copies/ml). The patient received Ganciclovir. CONCLUSION: Usually CMV infected patients present with renal dysfunction after renal transplantation but other organ involvements must not be ignored. We report a patient presenting only with intestinal signs and symptoms of CMV infection.
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spelling pubmed-36633172013-05-30 Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation Merrikhi, Ali-Reza Amir-Shahkarami, Seyed-Mohammad Saneian, Hosein Iran J Pediatr Case Report BACKGROUND: Cytomegalovirus is an important infection in kidney Transplantation. Isolation of the CMV virus or detection of its proteins or nucleic acid in any body fluid or tissue specimen is defined as “CMV infection”. CASE PRESENTATION: A 10-year-old girl was admitted frequently for vomiting and colicky watery diarrhea starting one month after renal transplantation from a non-relative living donor. Cr, BUN, serum electrolytes and also liver function tests were normal. Anti CMV IgM titer was negative before and after transplantation. On colonoscopy large aphthous like lesions were detected in the colon. CMV PCR of the lesion was strongly positive (>2000 copies/ml). The patient received Ganciclovir. CONCLUSION: Usually CMV infected patients present with renal dysfunction after renal transplantation but other organ involvements must not be ignored. We report a patient presenting only with intestinal signs and symptoms of CMV infection. Tehran University of Medical Sciences 2013-04 /pmc/articles/PMC3663317/ /pubmed/23724187 Text en © 2013 Iranian Journal of Pediatrics & Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
Merrikhi, Ali-Reza
Amir-Shahkarami, Seyed-Mohammad
Saneian, Hosein
Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title_full Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title_fullStr Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title_full_unstemmed Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title_short Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation
title_sort cytomegalovirus colitis in a 10 year-old girl after kidney transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663317/
https://www.ncbi.nlm.nih.gov/pubmed/23724187
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