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Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity

Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lym...

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Detalles Bibliográficos
Autores principales: Duarte-Williamson, Emilia, Antony, Fiona, Rotarescu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Derm101.com 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663349/
https://www.ncbi.nlm.nih.gov/pubmed/23785592
http://dx.doi.org/10.5826/dpc.0202a04
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author Duarte-Williamson, Emilia
Antony, Fiona
Rotarescu, Radu
author_facet Duarte-Williamson, Emilia
Antony, Fiona
Rotarescu, Radu
author_sort Duarte-Williamson, Emilia
collection PubMed
description Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established.
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spelling pubmed-36633492013-06-19 Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity Duarte-Williamson, Emilia Antony, Fiona Rotarescu, Radu Dermatol Pract Concept Observation Sinus histiocytosis is a rare inflammatory disease mainly affecting the cervical lymph nodes, presenting with skin lesions in 10% of cases. Our patient had a solitary nodule on the trunk without any other clinical signs. The histology reported a dermal neoplasm composed mainly of macrophages and lymphocytes. Macrophages were aggregated in clusters resembling lymph node sinuses. Lymphophagocytosis or emperipolesis (the presence of an intact cell within the cytoplasm of another cell) was noted and the diagnosis of sinus histiocytosis established. Derm101.com 2012-04-30 /pmc/articles/PMC3663349/ /pubmed/23785592 http://dx.doi.org/10.5826/dpc.0202a04 Text en Copyright: ©2012 Duarte-Williamson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Observation
Duarte-Williamson, Emilia
Antony, Fiona
Rotarescu, Radu
Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_full Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_fullStr Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_full_unstemmed Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_short Sinus histiocytosis (Rosai-Dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
title_sort sinus histiocytosis (rosai-dorfman disease) presenting with solitary cutaneous nodule: a very rare clinical entity
topic Observation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663349/
https://www.ncbi.nlm.nih.gov/pubmed/23785592
http://dx.doi.org/10.5826/dpc.0202a04
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