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Profile of perampanel and its potential in the treatment of partial onset seizures

Perampanel (PER) is a novel antiepileptic compound that decreases neuronal excitability by modulating glutamatergic transmission through selective noncompetitive blockade of AMPA receptors. PER has been evaluated in three pivotal placebo-controlled randomized trials as adjunctive therapy in adult dr...

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Detalles Bibliográficos
Autores principales:	Rheims, Sylvain, Ryvlin, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663472/ https://www.ncbi.nlm.nih.gov/pubmed/23717043 http://dx.doi.org/10.2147/NDT.S30129

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