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Endomembrane H-Ras Controls Vascular Endothelial Growth Factor-induced Nitric-oxide Synthase-mediated Endothelial Cell Migration

We demonstrate for the first time that endomembrane-delimited H-Ras mediates VEGF-induced activation of endothelial nitric-oxide synthase (eNOS) and migratory response of human endothelial cells. Using thiol labeling strategies and immunofluorescent cell staining, we found that only 31% of total H-R...

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Detalles Bibliográficos
Autores principales:	Haeussler, Dagmar J., Pimentel, David R., Hou, Xiuyun, Burgoyne, Joseph R., Cohen, Richard A., Bachschmid, Markus M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663556/ https://www.ncbi.nlm.nih.gov/pubmed/23548900 http://dx.doi.org/10.1074/jbc.M112.427765

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