Intramolecular H-bonding interaction in angular 3-π-EWG substituted imidazo[1,2-a]pyridines contributes to conformational preference

BACKGROUND: The proton at position 5 of imidazo[1,2-a]pyridines substituted with an angular electron withdrawing group (EWG) at position 3, shows an unusual downfield chemical shift, which is usually explained in terms of a peri effect. However usage of this term is sometimes confusing. In this inve...

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Detalles Bibliográficos
Autores principales: Velázquez-Ponce, Manuel, Salgado-Zamora, Héctor, Jiménez-Vázquez, Hugo A, Campos-Aldrete, Maria Elena, Jiménez, Rogelio, Cervantes, Humberto, Hadda, Taibi Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663774/
https://www.ncbi.nlm.nih.gov/pubmed/23363878
http://dx.doi.org/10.1186/1752-153X-7-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663774/
https://www.ncbi.nlm.nih.gov/pubmed/23363878
http://dx.doi.org/10.1186/1752-153X-7-20

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