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Differences in the Signaling Pathways of α(1A)- and α(1B)-Adrenoceptors Are Related to Different Endosomal Targeting

AIMS: To compare the constitutive and agonist-dependent endosomal trafficking of α(1A)- and α(1B-)adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype. METHODS: Using CypHer5 technology and VSV-G epitope tagged α(1A)- and α(1B)-ARs sta...

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Detalles Bibliográficos
Autores principales:	Segura, Vanessa, Pérez-Aso, Miguel, Montó, Fermí, Carceller, Elena, Noguera, María Antonia, Pediani, John, Milligan, Graeme, McGrath, Ian Christie, D’Ocon, Pilar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663791/ https://www.ncbi.nlm.nih.gov/pubmed/23717684 http://dx.doi.org/10.1371/journal.pone.0064996

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