P-glycoprotein efflux pump plays an important role in Trypanosoma cruzi drug resistance

Drug resistance in protozoan parasites has been associated with the P-glycoprotein (Pgp), an energy-dependent efflux pump that transports substances across the membrane. Interestingly, the genes TcPGP1 and TcPGP2 have been described in Trypanosoma cruzi, although the function of these genes has not...

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Detalles Bibliográficos
Autores principales: Campos, Mônica Caroline Oliveira, Castro-Pinto, Denise Barçante, Ribeiro, Grazielle Alves, Berredo-Pinho, Márcia Moreira, Gomes, Leonardo Henrique Ferreira, da Silva Bellieny, Myrtes Santos, Goulart, Carla Marins, Echevarria, Áurea, Leon, Leonor Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663987/
https://www.ncbi.nlm.nih.gov/pubmed/23572046
http://dx.doi.org/10.1007/s00436-013-3398-z

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