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Mathematical modelling to restore circulating IGF-1 concentrations in children with Crohn's disease-induced growth failure: a pharmacokinetic study

OBJECTIVES: Children with Crohn's disease grow poorly, and inflammation depresses the response of insulin-like growth factor-1 (IGF-1) to growth hormone. Correcting the inflammation normalises growth velocity; however, removing inflammation cannot be achieved in all children. Our lack of unders...

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Detalles Bibliográficos
Autores principales:	Rao, A, Standing, J F, Naik, S, Savage, M O, Sanderson, I R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2013
Materias:	Paediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664353/ https://www.ncbi.nlm.nih.gov/pubmed/23793696 http://dx.doi.org/10.1136/bmjopen-2013-002737

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