A yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation

In Saccharomyces cerevisiae, the SUP70 gene encodes the CAG-decoding tRNA(Gln)(CUG). A mutant allele, sup70-65, induces pseudohyphal growth on rich medium, an inappropriate nitrogen starvation response. This mutant tRNA is also a UAG nonsense suppressor via first base wobble. To investigate the basi...

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Detalles Bibliográficos
Autores principales: Kemp, Alain J, Betney, Russell, Ciandrini, Luca, Schwenger, Alexandra C M, Romano, M Carmen, Stansfield, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664417/
https://www.ncbi.nlm.nih.gov/pubmed/23146061
http://dx.doi.org/10.1111/mmi.12096

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