Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature

Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and ra...

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Detalles Bibliográficos
Autores principales: Coop, H., Pettit, L., Boon, C., Ramachandra, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664474/
https://www.ncbi.nlm.nih.gov/pubmed/23738187
http://dx.doi.org/10.1155/2013/194690
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author Coop, H.
Pettit, L.
Boon, C.
Ramachandra, P.
author_facet Coop, H.
Pettit, L.
Boon, C.
Ramachandra, P.
author_sort Coop, H.
collection PubMed
description Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and radiotherapy. These cases add to the body of case reports that have shown benefit for concomitant chemoradiotherapy in urethral squamous cell carcinoma. They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities.
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spelling pubmed-36644742013-06-04 Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature Coop, H. Pettit, L. Boon, C. Ramachandra, P. Case Rep Urol Case Report Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and radiotherapy. These cases add to the body of case reports that have shown benefit for concomitant chemoradiotherapy in urethral squamous cell carcinoma. They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities. Hindawi Publishing Corporation 2013 2013-05-07 /pmc/articles/PMC3664474/ /pubmed/23738187 http://dx.doi.org/10.1155/2013/194690 Text en Copyright © 2013 H. Coop et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Coop, H.
Pettit, L.
Boon, C.
Ramachandra, P.
Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_full Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_fullStr Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_full_unstemmed Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_short Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_sort radical chemoradiotherapy for urethral squamous cell carcinoma: two case reports and a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664474/
https://www.ncbi.nlm.nih.gov/pubmed/23738187
http://dx.doi.org/10.1155/2013/194690
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AT boonc radicalchemoradiotherapyforurethralsquamouscellcarcinomatwocasereportsandareviewoftheliterature
AT ramachandrap radicalchemoradiotherapyforurethralsquamouscellcarcinomatwocasereportsandareviewoftheliterature

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