Cargando…
A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies
Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation wit...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664480/ https://www.ncbi.nlm.nih.gov/pubmed/23738166 http://dx.doi.org/10.1155/2013/590729 |
_version_ | 1782271109566038016 |
---|---|
author | Özcan, Muhammed Emin Altınöz, Meriç Adil Karadeli, Hasan Hüseyin Asil, Talip Koçer, Abdulkadir |
author_facet | Özcan, Muhammed Emin Altınöz, Meriç Adil Karadeli, Hasan Hüseyin Asil, Talip Koçer, Abdulkadir |
author_sort | Özcan, Muhammed Emin |
collection | PubMed |
description | Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti-β2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder. |
format | Online Article Text |
id | pubmed-3664480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36644802013-06-04 A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies Özcan, Muhammed Emin Altınöz, Meriç Adil Karadeli, Hasan Hüseyin Asil, Talip Koçer, Abdulkadir Case Rep Neurol Med Case Report Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti-β2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder. Hindawi Publishing Corporation 2013 2013-05-08 /pmc/articles/PMC3664480/ /pubmed/23738166 http://dx.doi.org/10.1155/2013/590729 Text en Copyright © 2013 Muhammed Emin Özcan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Özcan, Muhammed Emin Altınöz, Meriç Adil Karadeli, Hasan Hüseyin Asil, Talip Koçer, Abdulkadir A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title_full | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title_fullStr | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title_full_unstemmed | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title_short | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
title_sort | 17-year-old female with systemic lupus presents with complex movement disorder: possible relationship with antiribosomal p antibodies |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664480/ https://www.ncbi.nlm.nih.gov/pubmed/23738166 http://dx.doi.org/10.1155/2013/590729 |
work_keys_str_mv | AT ozcanmuhammedemin a17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT altınozmericadil a17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT karadelihasanhuseyin a17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT asiltalip a17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT kocerabdulkadir a17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT ozcanmuhammedemin 17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT altınozmericadil 17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT karadelihasanhuseyin 17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT asiltalip 17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies AT kocerabdulkadir 17yearoldfemalewithsystemiclupuspresentswithcomplexmovementdisorderpossiblerelationshipwithantiribosomalpantibodies |