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Intratumor Hypoxia Promotes Immune Tolerance by Inducing Regulatory T Cells via TGF-β1 in Gastric Cancer
Regulatory T cell (Treg)-mediated immunosuppression represents one of the crucial tumor immune evasion mechanisms and is a main obstacle for successful tumor immunotherapy. Hypoxia, a common feature of solid tumors, has been associated with potentiated immunosuppression, decreased therapeutic respon...
Autores principales: | Deng, Bin, Zhu, Ji-Min, Wang, Yi, Liu, Tao-Tao, Ding, Yan-Bing, Xiao, Wei-Ming, Lu, Guo-Tao, Bo, Ping, Shen, Xi-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664556/ https://www.ncbi.nlm.nih.gov/pubmed/23723999 http://dx.doi.org/10.1371/journal.pone.0063777 |
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