Detailed Topology Mapping Reveals Substantial Exposure of the “Cytoplasmic” C-Terminal Tail (CTT) Sequences in HIV-1 Env Proteins at the Cell Surface

Substantial controversy surrounds the membrane topology of the HIV-1 gp41 C-terminal tail (CTT). While few studies have been designed to directly address the topology of the CTT, results from envelope (Env) protein trafficking studies suggest that the CTT sequence is cytoplasmically localized, as in...

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Detalles Bibliográficos
Autores principales: Steckbeck, Jonathan D., Sun, Chengqun, Sturgeon, Timothy J., Montelaro, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664582/
https://www.ncbi.nlm.nih.gov/pubmed/23724133
http://dx.doi.org/10.1371/journal.pone.0065220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664582/
https://www.ncbi.nlm.nih.gov/pubmed/23724133
http://dx.doi.org/10.1371/journal.pone.0065220

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