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The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition
One of the most important mechanisms that promotes metastasis is the stabilization of Hif-1 (hypoxia-inducible transcription factor 1). We decided to test whether Hif-1α also was required for early embryonic development. We focused our attention on the development of the neural crest, a highly migra...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664719/ https://www.ncbi.nlm.nih.gov/pubmed/23712262 http://dx.doi.org/10.1083/jcb.201212100 |