Skin Stem Cell Hypotheses and Long Term Clone Survival – Explored Using Agent-based Modelling

Epithelial renewal in skin is achieved by the constant turnover and differentiation of keratinocytes. Three popular hypotheses have been proposed to explain basal keratinocyte regeneration and epidermal homeostasis: 1) asymmetric division (stem-transit amplifying cell); 2) populational asymmetry (pr...

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Detalles Bibliográficos
Autores principales: Li, X., Upadhyay, A. K., Bullock, A. J., Dicolandrea, T., Xu, J., Binder, R. L., Robinson, M. K., Finlay, D. R., Mills, K. J., Bascom, C. C., Kelling, C. K., Isfort, R. J., Haycock, J. W., MacNeil, S., Smallwood, R. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664904/
https://www.ncbi.nlm.nih.gov/pubmed/23712735
http://dx.doi.org/10.1038/srep01904

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