Lytic and sclerotic (mixed) vertebral metastasis in ganglioneuroblastoma

The clinical presentation of ganglioneuroblastoma is highly variable and it is not uncommon to see metastasis at presentation. Bone is the second most common site of metastasis in neuroblastoma. Neuroblastoma cells usually activate osteoclasts and form osteolytic lesions. Here, we describe a patient...

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Detalles Bibliográficos
Autores principales: Sridhar, Subbiah, Bhadada, Sanjay Kuamr, Bhansali, Anil, Bhattacharya, Anish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665142/
https://www.ncbi.nlm.nih.gov/pubmed/23723589
http://dx.doi.org/10.4103/0972-3919.110721
Descripción
Sumario:The clinical presentation of ganglioneuroblastoma is highly variable and it is not uncommon to see metastasis at presentation. Bone is the second most common site of metastasis in neuroblastoma. Neuroblastoma cells usually activate osteoclasts and form osteolytic lesions. Here, we describe a patient who presented with back pain. On evaluation, X-ray and positron emission tomography-computed tomography showed mixed lytic and sclerotic vertebral metastasis, and subsequently diagnosed as ganglioneuroblastoma.

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