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RUNX3 gene promoter demethylation by 5-Aza-CdR induces apoptosis in breast cancer MCF-7 cell line

Runt-related transcription factor 3 (RUNX3) is a tumor suppressor gene, its inactivation due to hypermethylation related to carcinogenesis. The aim of this study was to investigate the effects of 5-aza-2′-deoxycytidine (5-Aza-CdR) on cell proliferation and apoptosis by demethylation of the promoter...

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Detalles Bibliográficos
Autores principales:	Kang, Hua-Feng, Dai, Zhi-Jun, Bai, He-Ping, Lu, Wang-Feng, Ma, Xiao-Bin, Bao, Xing, Lin, Shuai, Wang, Xi-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665559/ https://www.ncbi.nlm.nih.gov/pubmed/23723708 http://dx.doi.org/10.2147/OTT.S43744

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