TRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavages

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive malignancy closely associated with asbestos exposure and extremely resistant to current treatments. It exhibits a steady increase in incidence, thus necessitating an urgent development of effective new treatments. METHODS: Proteasome...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Bao-Zhu, Chapman, Joshua, Ding, Min, Wang, Junzhi, Jiang, Binghua, Rojanasakul, Yon, Reynolds, Steven H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665596/
https://www.ncbi.nlm.nih.gov/pubmed/23517112
http://dx.doi.org/10.1186/1471-2407-13-140

Ejemplares similares

Ejemplares similares