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Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer

BACKGROUND: Estrogen metabolism-mediated oxidative stress is suggested to play an important role in estrogen-induced breast carcinogenesis. We have earlier demonstrated that antioxidants, vitamin C (Vit C) and butylated hydroxyanisole (BHA) inhibit 17β-estradiol (E2)-mediated oxidative stress and ox...

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Detalles Bibliográficos
Autores principales:	Singh, Bhupendra, Chatterjee, Anwesha, Ronghe, Amruta M, Bhat, Nimee K, Bhat, Hari K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665669/ https://www.ncbi.nlm.nih.gov/pubmed/23697596 http://dx.doi.org/10.1186/1471-2407-13-253

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