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Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα(12/13)-Rho-Rac1 pathway

BACKGROUND: Ovarian cancer G protein coupled receptor 1 (OGR1) mediates inhibitory effects on cell migration in human prostate and ovarian cancer cells. However, the mechanisms and signaling pathways that mediate these inhibitory effects are essentially unknown. METHODS: MCF7 cell line was chosen as...

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Detalles Bibliográficos
Autores principales:	Li, Jing, Guo, Bin, Wang, Jing, Cheng, Xiaoyan, Xu, Yan, Sang, Jianli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665705/ https://www.ncbi.nlm.nih.gov/pubmed/23663350 http://dx.doi.org/10.1186/1750-2187-8-6

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